Duloxetine HCl (S)

SKU: orb1308539

Description

Duloxetine hydrochloride is an (S)-enantiomer thiophene derivative that acts as a selective serotonin and norepinephrine reuptake inhibitor (SNRI). It is utilized in research as an antidepressant and anxiolytic agent and for studying neuropathic pain mechanisms in models of diabetes and fibromyalgia, supporting both in vitro and in vivo experimental applications.

Research Area

Neuroscience

Key Properties

• CAS Number: 136434-34-9
• MW: 333.9
• Purity: >98%
• Formula: C₁₈H₁₉NOS · HCl
• SMILES: s1cccc1[C@@H](Oc1cccc2c1cccc2)CCNC.Cl
• Target: Monoamine transporter
• Solubility: Soluble in DMSO (up to 25 mg/ml)

Bioactivity

• Target IC50:
  SNRI:4.6 nM(Ki)

Storage & Handling

• Storage: RT
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

LY248686

Compound Identifiers

PubChem CID

60834