DT-6

SKU: orb2277682

Description

DT-6 is a potent small molecule inhibitor of TGF-β1. It blocks M2 macrophage-driven epithelial-mesenchymal transition (EMT) and cancer cell invasion, making it a valuable tool for studying tumor metastasis and the tumor microenvironment in both in vitro and in vivo cancer research.

Research Area

Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2414315-95-8
• MW: 2008.23
• Formula: C₈₉H₁₃₀N₂₀O₂₉S₂
• SMILES: O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2OCC(NCCCCCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC=4C=5C(NC4)=CC=CC5)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(N)=O)C(O)=O)=O)CCC(N)=O)=O)CCSC)=O)CCSC)=O)C)=O)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CO)=O)C)=O)CC(O)=O)=O)CC(C)C)=O)CO)=O)[C@@H](C)O)=O)=O
• Target: TGF-beta/Smad

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168510615