DSPE-PEG-Biotin (MW 2000)

SKU: orb1307453

Description

This heterobifunctional PEG linker, featuring DSPE and biotin termini, is designed for constructing PROTAC molecules. Its amphiphilic nature facilitates the synthesis of targeted protein degraders for research in both cellular and in vivo models, aiding the study of protein function and therapeutic pathways.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 385437-57-0
• MW: 1000(Average)
• Purity: 95.00% (May vary between batches)
• Target: Liposome

Bioactivity

• In Vitro:
  PROTACs consist of two ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets the desired protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DSPE-PEG-Biotin, DSPEPEGBiotin (MW 2000), DSPE PEG Biotin (MW 2000), PROTAC Linker, PROTACLinker, PEGs

Quick Database Links

Gene Symbol

Liposome