DS44960156

SKU: orb1692704

Description

DS44960156 is a novel small molecule inhibitor targeting methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) with additional activity against MTHFD1. This dual inhibitor is a valuable research tool for investigating cancer metabolism, supporting both in vitro and in vivo studies of tumor cell proliferation and one-carbon pathway dysregulation.

Research Area

Cell Biology, Metabolism Research, Molecular Biology

Key Properties

• CAS Number: 2361327-08-2
• MW: 349.34
• Purity: 99.13% (May vary between batches)
• Formula: C₂₀H₁₅NO₅
• SMILES: OC(=O)c1ccc(cc1)C(=O)N1CCc2c(C1)c(=O)oc1ccccc21
• Target: DHFR,Dehydrogenase
• Solubility: Methanol:soluble;DMSO:soluble

Bioactivity

• Target IC50:
  MTHFD1:>30 μM|MTHFD2:1.6 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

MTHFD1, MTHFD2, DS 44960156, DS44960156, DS-44960156

Compound Identifiers

PubChem CID

138393352