Drofenine hydrochloride

SKU: orb1310359

Description

Drofenine hydrochloride, also known as Hexahydroadiphenine hydrochloride, is a potent and competitive butyrylcholinesterase (BChE) inhibitor with a Ki of 3 µM. This small molecule is a valuable research tool for studying cholinergic signaling in vitro and has been utilized in experimental models investigating BChE's role in metabolic processes.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 548-66-3
• MW: 353.93
• Purity: 99.45% (May vary between batches)
• Formula: C₂₀H₃₁NO₂·HCl
• SMILES: Cl.CCN(CC)CCOC(=O)C(C1CCCCC1)c1ccccc1
• Target: Cholinesterase (ChE)
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.65 mM);DMSO:15 mg/mL (42.38 mM)

Bioactivity

• Target IC50:
  BChE:3 μM(ki)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cholinesterase (ChE), Drofenine, Drofenine hydrochloride, Drofenine Hydrochloride, AChE, Hexahydroadiphenine, Hexahydroadiphenine hydrochloride, Hexahydroadiphenine Hydrochloride, Inhibitor, inhibit

Compound Identifiers

PubChem CID

92806