DQ661

SKU: orb2945773

Description

DQ661 is a dimeric quinacrine-based compound that potently inhibits PPT1 and autophagy. It suppresses mTORC1 activity, reducing pS6K T389 and pS6 S240/244 protein levels, and demonstrates anticancer properties in research models. This small molecule is used in studies investigating autophagy, mTOR signaling, and oncology in both cellular and in vivo experiments.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2027551-01-3
• MW: 712.75
• Formula: C₄₁H₄₇Cl₂N₅O₂
• SMILES: ClC=1C=CC=2C(=NC=3C=CC(OC)=CC3C2NCCCCCCN(C)CCCCCCNC4=C5C=CC(Cl)=CC5=NC=6C=CC(OC)=CC64)C1
• Target: mTOR,Autophagy

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

122633440