DPP-4-IN-17

SKU: orb3136576

Description

DPP-4-IN-17 is an orally active and selective inhibitor of dipeptidyl peptidase-4 (DPP-4) with an IC50 value of 0.12 nM. It increases the enzyme's Km value (75.73 μM compared to the substrate alone at 27.18 μM) and reduces catalytic efficiency. In Streptozotocin (STZ)/Nicotinamide (NA)-induced diabetic rats, DPP-4-IN-17 lowers blood glucose levels and reverses weight loss. This compound is useful for research in type 2 diabetes (T2DM).

Research Area

Immunology & Inflammation, Protein Biochemistry

Key Properties

• Target: DPP-4

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

DPP-4