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Doramapimod

SKU: orb1225432

Description

A highly potent p38 MAPK inhibitor with Kd of 0.1 nM; displays no activity on ERK1, IKK2b, ZAP-70, EGFR, PKA, PKC, etc.; shows inhibition of TNFα inTHP.1 with IC50 of 18 nM; orally active.

Images & Validation

Key Properties

CAS Number285983-48-4
MW527.6572
Purity>98% (HPLC)
FormulaC31H37N5O3
SMILESO=C(NC1=C2C=CC=CC2=C(OCCN3CCOCC3)C=C1)NC4=CC(C(C)(C)C)=NN4C5=CC=C(C)C=C5
Targetp38 MAPK
Solubility10 mM in DMSO

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

BIRB 796 | BIRB-796 | BIRB796

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Doramapimod (orb1225432)

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Available Sizes

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5 mg
$ 70.00
10 mg
$ 100.00
25 mg
$ 130.00
50 mg
$ 150.00
100 mg
$ 200.00
200 mg
$ 340.00
500 mg
$ 540.00