Dolastatin 10 trifluoroacetate

SKU: orb1704640

Description

Dolastatin 10 TFA is a marine-derived antimitotic agent that potently inhibits tubulin polymerization and non-competitively blocks vincristine binding. It is widely used in cancer research, demonstrating potent antitumor activity in both in vitro cytotoxicity assays and in vivo xenograft models.

Key Properties

• MW: 899.11
• Formula: C₄₄H₆₉F₃N₆O₈S
• SMILES: CC[C@]([C@@](N(C([C@](/N=C(O)/[C@](N(C)C)([H])C(C)C)([H])C(C)C)=O)C)([H])[C@@](OC)([H])CC(N1CCC[C@@]1([H])[C@@](OC)([H])[C@@](/C(O)=N/[C@@](C2=NC=CS2)([H])CC3=CC=CC=C3)([H])C)=O)([H])C.FC(F)(C(O)=O)F
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

121513847