Dolasetron Mesylate

SKU: orb1306009

Description

Dolasetron Mesylate is a selective 5-HT3 receptor antagonist used in research to investigate mechanisms and treatments for chemotherapy-induced nausea and vomiting. Its application extends to both in vitro receptor binding studies and in vivo models for evaluating antiemetic efficacy.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 115956-13-3
• MW: 420.48
• Purity: >99.99% (May vary between batches)
• Formula: C₂₀H₂₄N₂O₆S
• SMILES: O.CS(O)(=O)=O.[H][C@]12C[C@@H](C[C@@H]3CC(C1)C(=O)CN23)OC(=O)c1c[nH]c2ccccc12
• Target: 5-HT Receptor
• Solubility: DMSO:60 mg/mL (142.69 mM);H2O:25 mg/mL (59.46 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

5-hydroxytryptamine Receptor, 5HTReceptor, 5-HT3, 5HT Receptor, 5-HT Receptor, Anzemet hydrate, Anzemet Hydrate, Dolasetron, Dolasetron Mesylate, inhibit, Inhibitor, MDL-73147EF, Serotonin Receptor

Compound Identifiers

PubChem CID

6918119