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DNMT-IN-5

SKU: orb3135682

Description

DNMT-IN-5 is a potent and stable inhibitor of DNA methyltransferase (DNMT), with an IC50 of 0.78 nM. It exhibits submicromolar inhibitory activity against DNMT3A, upregulates the expression of target genes, inhibits cell proliferation, and induces key cell cycle arrest. DNMT-IN-5 is suitable for research on p53-deficient colorectal cancer.

Research Area

Epigenetics & Chromatin

Images & Validation

Key Properties

TargetDNA Methyltransferase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

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Protocol Information