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DNH28

SKU: orb3135945

Description

DNH28 is a potent NF-κB and MAPK inhibitor with an IC50 value of 0.93 μM in HepG2 cells. It induces apoptosis by downregulating Bcl-2 and upregulating BAX and Cleaved-caspase-3 expression. DNH28 can arrest the cell cycle and inhibit cell migration, and is applicable for research in hepatocellular carcinoma (HCC).

Research Area

Cell Biology, Protein Biochemistry, Signal Transduction

Images & Validation

Key Properties

TargetCaspase,p38 MAPK,Bcl-2 Family,NF-κB,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information