DNA ligase-IN-2

SKU: orb2945673

Description

DNA ligase-IN-2 is a potent inhibitor of Staphylococcus aureus LigA, exhibiting an IC50 of 29 nM against its adenylation activity. It demonstrates potent anti-staphylococcal activity in vitro (MIC = 1 µg/mL) while showing significantly less activity against E. coli. This inhibitor is a valuable tool for studying bacterial DNA replication and ligase-targeted antibacterial research.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology

Key Properties

• CAS Number: 635681-64-0
• MW: 273.219
• Formula: C₁₃H₈FN₃O₃
• SMILES: O=C(N)C1=CC=2C(=O)C3=CC(F)=CC=C3OC2N=C1N
• Target: Antibacterial,DNA/RNA Synthesis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

10038928