DMH4

SKU: orb1704566

Description

DMH4 is a highly selective small molecule inhibitor targeting VEGFR2 (KDR), exhibiting potent activity with an IC50 of 160 nM. It is a valuable research tool for studying angiogenesis and VEGFR2 signaling pathways in both cellular and animal models of cancer and other vascular diseases.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 515880-75-8
• MW: 400.47
• Purity: 99.58% (May vary between batches)
• Formula: C₂₄H₂₄N₄O₂
• SMILES: C(CN1CCOCC1)Oc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccccc1
• Target: VEGFR
• Solubility: 10% DMSO+40% PEG300+5% Tween-80+45% Saline:0.5 mg/mL (1.25 mM);DMSO:9 mg/mL (22.47 mM)

Bioactivity

• Target IC50:
  VEGFR2:0.16 μM (IC50)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

VEGFR2, DMH 4, DMH4, DMH-4

Compound Identifiers

PubChem CID

5329447