DLPC

SKU: orb1306315

Description

DLPC is a phospholipid compound that acts as an agonist for the nuclear receptor LRH-1. It is utilized in biological research to study LRH-1 signaling pathways in metabolic regulation, inflammation, and stem cell biology, with applications in both in vitro and in vivo experimental models.

Research Area

Cell Biology, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 18194-25-7
• MW: 621.83
• Purity: 99.94%
• Formula: C₃₂H₆₄NO₈P
• SMILES: CCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCC
• Target: PPAR,Others,Orphan Receptor,TNF,Liposome,Apoptosis
• Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:7.14 mg/mL (11.48 mM);Ethanol:125 mg/mL (201.02 mM)

Bioactivity

• In Vivo:
  DLPC treatment induces bile acid biosynthetic enzymes in mouse liver, increases bile acid levels, and lowers hepatic triglycerides and serum glucose. DLPC treatment also decreases hepatic steatosis and improves glucose homeostasis in two mouse models of insulin resistance.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, liver receptor homolog-1 (LRH1, NR5A2), Inhibitor, 1,2 Dilauroyl sn glycero 3 phosphocholine, 1,2Dilauroylsnglycero3phosphocholine, DLPC

Compound Identifiers

PubChem CID

512874