DLK-IN-2

SKU: orb3210703

Description

DLK-IN-2 is a selective inhibitor of DLK and acts as a neuroprotective agent. It shows no significant inhibitory effect on CYP enzymes 3A4, 2D6, and 2C9. DLK-IN-2 inhibits acute axonal palmitoylation of DLK, blocks DLK-dependent prodegenerative axon-to-cell body retrograde signaling, and suppresses c-Jun phosphorylation. It is used for studying mechanisms in neurodegenerative diseases.

Key Properties

• CAS Number: 883012-32-6
• MW: 444.97
• Formula: C₂₃H₂₅ClN₂O₃S
• SMILES: O=C(NC1=CC=C(C=C1)S(=O)(=O)NC23CC4CC(CC(C4)C2)C3)C5=CC=C(Cl)C=C5
• Target: MAPK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

MAPK