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DL78

SKU: orb3174267

Description

DL78 is a potent antimitotic agent that induces mitotic arrest, mitotic catastrophe, and apoptosis in cancer cells by disrupting the interaction between Myc and α-tubulin. It exhibits broad anticancer activity, particularly targeting cancer cells characterized by chromosomal instability and MYC overexpression. In the OV81.2 xenograft model, DL78 significantly reduces tumor burden. DL78 can be employed in ovarian cancer research.

Research Area

Cell Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number132993-79-4
MW336.34
FormulaC20H16O5
SMILESO=C(C=1OC=2C=CC(OC)=CC2C1)C3=C(OC=4C=CC(OC)=CC43)C
Targetc-Myc,Apoptosis,Microtubule Associated

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information