DL-Pyroglutamic acid

SKU: orb1940222

Description

DL-Pyroglutamic acid exhibited a strong inactivating effect on hepatitis B surface antigen.

Images & Validation

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Key Properties

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CAS Number	149-87-1
MW	129.114
Purity	>98% (HPLC)
Formula	C₅H₇NO₃
SMILES	O=C(O)C(CC1)NC1=O
Target	Pyroptosis\|Caspase-1\|IL-1β\|inflammation
Solubility	In Vitro: DMSO : 100 mg/mL (774.53 mM)

Bioactivity

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In Vivo	DL-Pyroglutamic acid (0.775 mM/L) completely abolishes the myoclonic jerks and EEG spikes in rats model of epileptic by cobalt implantation in the sensorimotor cerebral cortex.
In Vitro	DL-Pyroglutamic acid results 50 and 100% inactivation of the antigen of 0.01-0.025% and 0.025-0.05%, respectively. DL-Pyroglutamic acid is a possible glutamate antagonist, blocks glutamate miniature-end-plate potential in locust muscle-Druce and Bradford.

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Quick Database Links

Gene Symbol

Pyroptosis|Caspase-1|IL-1β|inflammation

Protocol Information

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