DL-Mevalonolactone

SKU: orb1224281

Description

Mevalonic acid is very soluble in water and polar organic solvents. It exists in equilibrium with its lactone form, called mevalonolactone, that is formed by internal condensation of its terminal alcohol and carboxylic acid functional groups.

Key Properties

• CAS Number: 674-26-0
• MW: 130.14
• Purity: >98% (HPLC)
• Formula: C₆H₁₀O₃
• SMILES: CC1(O)CCOC(=O)C1
• Target: Others
• Solubility: Limited solubility

Bioactivity

• In Vivo:
  Animal model: C57BL/6 mice with cerivastatin/simvastatin induced myopathy. Dosage: 200 mg/kg. Administration: oral gavage. Result: Increased muschle strength and endurance in hanging wire and grip tests.
• In Vitro:
  Real Time qPCR Cell line: U87-MG. Concentration: 0.1-1 mM Incubation time: 72 h. Result: Increased SOD, HemeOX and IL1B expression

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DL-Mevalonic Acid Lactone | (±)-Mevalonolactone | NSC 90804

Quick Database Links

Gene Symbol

Others