DKFZ-633

SKU: orb3211441

Description

DKFZ-633 is a potent inhibitor of KLK6 and a KLK6-specific probe, exhibiting an IC50 of 250 nM against human KLK6. It selectively covalently labels the active state of KLK6, allowing for the successful pull-down and capture of endogenous active KLK6 from conditioned cell media. DKFZ-633 serves as an important tool for studying the function and regulatory mechanisms of KLK6 in head and neck cancer.

Key Properties

• CAS Number: 2244425-14-5
• MW: 440.49
• Formula: C₂₆H₂₄N₄O₃
• SMILES: O=C(OCC(=O)NC=1C(=NN(C=2C=CC=CC2)C1C)C)CC=3C=4C=C(C#C)C=CC4NC3C
• Target: Serine Protease

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Serine Protease