Ditiocarb sodium

SKU: orb1220631

Description

Ditiocarb sodium (Sodium diethyldithiocarbamate) is an accelerator of the rate of copper cementation. Sodium diethyldithiocarbamate reduces the incidence of HIV infection.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 148-18-5
• MW: 171.26
• Purity: >98% (HPLC)
• Formula: C₅H₁₀NNaS₂
• SMILES: [Na+].CCN(CC)C([S-])=S
• Target: HIV
• Solubility: DMSO:300 mg/mL (1751.72 mM)

Bioactivity

• In Vivo:
  Ditiocarb sodium (Sodium diethyldithiocarbamate) improves the depressed immune responses of newborn and aged mice. Sodium diethyldithiocarbamate prevents cisplatin nephrotoxicity in animals without reducing the antitumor activity. In that AIDS model, Ditiocarb sodium reduces lymphadenopathy and hypergammaglobulinemia, restores immunocompetence, and prolongs survival.
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• In Vitro:
  Ditiocarb sodium (Sodium diethyldithiocarbamate) reacts with the Cu2+ solution giving a complex of copper diethyldithiocarbamate, which enhances the rate of cementation. Ditiocarb sodium is an agent with strong antioxidant capacity and chelating activities.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Sodium diethyldithiocarbamate

Quick Database Links

Gene Symbol

HIV