Disitertide acetate

SKU: orb1709860

Description

Disitertide acetate (P144 acetate) is a peptide-based inhibitor that selectively blocks TGF-β1 signaling by disrupting its receptor interaction. It also exhibits PI3K inhibitory activity and can induce apoptosis, making it a useful tool for studying fibrotic diseases and cancer in both cellular and animal models.

Research Area

Stem Cell & Developmental Biology

Key Properties

• Target: TGF-beta/Smad
• MW: 1640.88
• Purity: 95.11% (May vary between batches)
• Formula: C₇₀H₁₁₃N₁₇O₂₄S₂
• SMILES: C[C@@H](O)[C@H](N)C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N[C@@H](CO)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(N[C@@H](C)C(N[C@@H](CCSC)C(N[C@@H](CCSC)C(N[C@@H](CCC(N)=O)C(N[C@H](C(O)=O)CC(N)=O)=O)=O)=O)=O)=O)CC1=CNC2=CC=CC=C12)=O)=O)=O)=O)=O)=O)=O)=O.CC(O)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Disitertide Acetate, Disitertide acetate(272105-42-7 Free base), P144 acetate, P144 Acetate, P-144 Acetate, P 144 Acetate, Smad, TGFβ1, TGF-beta, TGFbeta/Smad, TGFβ, TGF-β/Smad, TGFb, TGF-b/Smad, TGFbeta

Compound Identifiers

PubChem CID

166600458