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Direct Violet 1

SKU: orb1218264

Description

Direct Violet 1 is an agent of dye.

Images & Validation

Key Properties

CAS Number2586-60-9
MW728.66
Purity>98% (HPLC)
FormulaC32H22N6Na2O8S2
SMILESO=S(C1=CC(O)=C2C(N=NC3=CC=C(C4=CC=C(N=NC5=C(N)C=CC6=CC(S(=O)([O-])=O)=CC(O)=C56)C=C4)C=C3)=C(N)C=CC2=C1)([O-])=O.[Na+].[Na+]
TargetOthers
SolubilityDMSO:Soluble

Bioactivity

In Vitro
Direct Violet 1 inhibits SARS-CoV-2-S-RBD binding to human ACE2, inhibits SARS-CoV-S1S2 binding to ACE2, and inhibits TNF-R1 binding to TNFα with IC50 values of 1.47 μM, 2.63 μM, and 2.11 μM, respectively. Direct Violet 1 inhibits SARS-CoV-2 pseudovirus entry into hACE2 expressing host cells in a concentration-dependent manner with an IC50 of 35.8 μM.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Airedale Violet ND | CCRIS 2413 | NSC 75778 | NSC-75778 | NSC75778 | Direct Violet N

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  • Direct Violet 1 [orb1306775]

    ≥98%

    2586-60-9

    728.66

    C32H22N6Na2O8S2

    1 ml x 10 mM (in DMSO), 1 g
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Protocol Information

Direct Violet 1 (orb1218264)

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