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Dipotassium glycyrrhizinate

SKU: orb1220687

Description

Dipotassium glycyrrhizinate is an anionic surfactant having anti-allergic and anti-inflammatory activities.

Images & Validation

Key Properties

CAS Number68797-35-3
MW899.12
Purity>98% (HPLC)
FormulaC42H60K2O16
SMILES[K+].[K+].[H][C@@]12C[C@](C)(CC[C@]1(C)CC[C@]1(C)C2=CC(=O)[C@]2([H])[C@@]3(C)CC[C@H](O[C@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)C([O-])=O)C([O-])=O)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O
TargetOthers
SolubilityDMSO:25 mg/mL (27.8 mM)

Bioactivity

In Vivo
Animal model: Iodine-induced murine model of autoimmune thyroiditis. Dosage: 50 mg/kg. Administration: i.p. , once daily for 4 weeks. Result: Reduced serum levels of TgAb, HMGB1, TNF-α, IL-6, IL-1β. Decreased The prevalence of thyroiditis and the infiltration of lymphocytes, and attenuated the severity of thyroiditis.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Dipotassium glycyrrhizinate (orb1220687)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

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% Tween 80 +
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