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Di(MMY-SJG)-Ph-prop-2-yne-1-sulfonic acid

SKU: orb3181679

Description

Di(MMY-SJG)-Ph-prop-2-yne-1-sulfonic acid (Compound 5) is a cytotoxic pyrrolobenzodiazepine (PBD) dimer derivative. It exhibits moderate DNA alkylation activity and can serve as a payload for antibody-drug conjugates (ADCs), demonstrating potent antigen-dependent cytotoxicity.

Research Area

Cell Biology, Molecular Biology

Images & Validation

Key Properties

CAS Number3037777-07-1
MW736.8
FormulaC39H36N4O9S
SMILESO=C1C=2C(=CC(OCC3=CC(COC4=C(OC)C=C5C(=C4)N=C[C@]6(N(C5=O)CC(=C)C6)[H])=CC(C#CCS(=O)(=O)O)=C3)=C(OC)C2)N=C[C@]7(N1CC(=C)C7)[H]
TargetADC Cytotoxin,DNA/RNA Synthesis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information