Dimethyl-W84 (dibromide)

SKU: orb1692300

Description

Dimethyl-W84 is a potent and selective allosteric modulator of the M2 muscarinic acetylcholine receptor (EC₅₀ = 3 nM), which slows the dissociation of orthosteric ligands like N-methylscopolamine. It is a valuable research tool for investigating GPCR allostery in vitro and is used in studies of cardiac and neuronal signaling pathways.

Research Area

Neuroscience

Key Properties

• CAS Number: 402475-33-6
• MW: 736.59
• Formula: C₃₄H₄₈Br₂N₄O₄
• SMILES: [Br-].[Br-].Cc1ccc2C(=O)N(CCC[N+](C)(C)CCCCCC[N+](C)(C)CCCN3C(=O)c4ccc(C)cc4C3=O)C(=O)c2c1
• Target: AChR,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

44265577