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Dimesna

SKU: orb1307813

Description

Dimesna

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number16208-51-8
MW326.34
Purity99.76% (May vary between batches)
FormulaC4H8Na2O6S4
SMILES[O-]S(=O)(=O)CCSSCCS(=O)(=O)[O-].[Na+].[Na+]
TargetOthers
SolubilityDMSO:13 mg/mL (39.84 mM)

Bioactivity

In Vivo
Dimesna modulated paclitaxel-induced MTP hyperpolymerization, and mesna, an in vivo metabolite of Dimesna, prevented cisplatin-induced MTP inactivation. The renal organic anion transporter proteins OAT1 (KM=636 μM), OAT3 (KM=390 μM) and OAT4 (KM=590 μM) were able to specifically bind Dimesna.
In Vitro
Dimesna modulated paclitaxel-induced MTP hyperpolymerization, and mesna, an in vivo metabolite of Dimesna, prevented cisplatin-induced MTP inactivation. The renal organic anion transporter proteins OAT1 (KM=636 μM), OAT3 (KM=390 μM) and OAT4 (KM=590 μM) were able to specifically bind Dimesna.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Dimesna, BNP 7787, BNP7787, BNP-7787, organic anion transporter, inhibit, Inhibitor

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Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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1 ml x 10 mM (in DMSO)
$ 70.00
100 mg
$ 80.00
500 mg
$ 150.00
1 g
$ 200.00
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