Dihydrolycorine

SKU: orb1221941

Description

Dihydrolycorine-HCL(DL) shows hypotensive effects, it can block alpha 1-adrenoceptors. Dihydrolycorine is an inhibitors of protein synthesis in eukarytic cells, it halts protein synthesis in eukaryotic cells by inhibiting the peptide bone formation step. Dihydrolycorine and nimodipine protects against anoxia damage of brain in rat.

Key Properties

• CAS Number: 6271-21-2
• MW: 289.33
• Purity: >98% (HPLC)
• Formula: C₁₆H₁₉NO₄
• SMILES: C1CN2CC3=CC4=C(C=C3C5C2C1CC(C5O)O)OCO4
• Target: Apoptosis
• Solubility: In Vitro: DMSO : 12.5 mg/mL (43.20 mM)

Bioactivity

• In Vivo:
  Dihydrolycorine inhibits methoxamine-induced contraction of isolated rabbit aortic rings and rat anococcygeus muscle with pA2 values of 5.93 and 6.35, respectively.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis