Difelikefalin (CR845)

SKU: orb611270

Description

Difelikefalin (CR-845; FE-202845) is a peripherally restricted and selective agonist of kappa opioid receptor (KOR). Difelikefalin produces anti-inflammatory effects and has the potential in modulating pruritus in conditions such as chronic kidney disease[1][2].

Key Properties

• CAS Number: 1024828-77-0
• MW: 679.85
• Purity: >98%
• Formula: C₃₆H₅₃N₇O₆
• SMILES: O=C(C1(N)CCN(C([C@@H](CCCCN)NC([C@@H](CC(C)C)NC([C@@H](CC2=CC=CC=C2)NC([C@@H](CC3=CC=CC=C3)N)=O)=O)=O)=O)CC1)O

Storage & Handling

• Disclaimer: For research use only