Didesethyl chloroquine

SKU: orb1709870

Description

Didesethyl chloroquine (Bisdesethylchloroquine) is the principal metabolite of chloroquine and acts as a myocardial inhibitor. It is utilized in pharmacological research to study cardiotoxicity mechanisms and metabolic pathways, both in vitro and in vivo.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 4298-14-0
• MW: 263.77
• Purity: >99.99% (May vary between batches)
• Formula: C₁₄H₁₈ClN₃
• SMILES: CC(CCCN)Nc1ccnc2cc(Cl)ccc12
• Target: Drug Metabolite
• Solubility: DMSO:90 mg/mL (341.21 mM)

Bioactivity

• Target IC50:
  P. falciparum (3D7):0.0553 μM|P. falciparum:58.3 μM|P. falciparum (PH3):1.2563 μM|P. falciparum (HB3):0.0472 μM|P. falciparum (K1):1.3386 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Drug Metabolite, Didesethyl chloroquine, DrugMetabolite, Bisdesethylchloroquine

Compound Identifiers

PubChem CID

122672