Dichotomine B

SKU: orb1680239

Description

Dichotomine B is a natural alkaloid that attenuates neuroinflammation by modulating the TLR4/MyD88-mTOR pathway in LPS/ATP-stimulated BV2 microglia. This compound is a useful research tool for studying neuroinflammatory mechanisms in vitro and has potential applications in research fields such as neuroscience and immunology.

Research Area

Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 755036-41-0
• MW: 272.26
• Formula: C₁₄H₁₂N₂O₄
• SMILES: [C@@H](CO)(O)C1=C2C(C=3C(N2)=CC=CC3)=CC(C(O)=O)=N1
• Target: MyD88,TLR,mTOR
• Solubility: 10% DMSO+90% Corn Oil:1 mg/mL (3.67 mM);DMSO:10 mg/mL (36.73 mM)

Storage & Handling

• Storage: keep away from direct sunlight,keep away from moisture,store at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Dichotomine B

Compound Identifiers

PubChem CID

11173314