DHX9-IN-2

SKU: orb1942202

Description

DHX9-IN-2 is a small molecule inhibitor of the ATP-dependent RNA helicase DHX9, applied in cancer research. It is utilized in oncology studies to investigate DHX9's role in transcription and genome stability, supporting both in vitro cellular assays and in vivo tumor model experiments.

Research Area

Cell Biology, Immunology & Inflammation, Molecular Biology

Key Properties

• CAS Number: 2973395-71-8
• MW: 421.92
• Purity: 98.00% (May vary between batches)
• Formula: C₁₈H₁₆ClN₃O₃S₂
• SMILES: O=C(NC1=CC(Cl)=CC(=C1)NS(=O)(=O)C)C=2SC=C(C2)C=3N=CC=CC3C
• Target: DNA/RNA Synthesis
• Solubility: DMSO:140 mg/mL (331.82 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.82 mM)

Bioactivity

• Target IC50:
  DHX9:0.0698 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DNASynthesis, DNA Synthesis, DNA/RNA Synthesis, ATX968, ATX-968, RNASynthesis, RNA Synthesis

Compound Identifiers

PubChem CID

169144997