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DHODH-IN-24

SKU: orb2566495

Description

DHODH-IN-24 (compound 16) is a potent small molecule inhibitor of human dihydroorotate dehydrogenase with an IC50 of 91 nM. This tool compound is suitable for in vitro enzymatic assays and cellular studies to investigate DHODH's role in pyrimidine biosynthesis, relevant for immunology and oncology research.

Research Area

Cell Biology, Metabolism Research, Molecular Biology

Images & Validation

Key Properties

CAS Number418775-30-1
MW394.51
FormulaC26H26N4
SMILESC(=NN(CCN(N=CC=1C2=C(C=CC1)C=CC=C2)C)C)C=3C4=C(C=CC3)C=CC=C4
TargetDehydrogenase,DNA/RNA Synthesis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information