DHA-paclitaxel

SKU: orb1739474

Description

DHA-paclitaxel (Taxoprexin) is a prodrug that conjugates paclitaxel to the fatty acid DHA for targeted tumor delivery. It inhibits microtubule disassembly and Bcl-2 function, blocking cell division and inducing apoptosis. This agent shows enhanced pharmacokinetics and antitumor efficacy in preclinical in vivo cancer models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 199796-52-6
• MW: 1164.38
• Formula: C₆₉H₈₁NO₁₅
• SMILES: O(C(C)=O)[C@]12[C@]3([C@H](OC(=O)C4=CC=CC=C4)[C@@]5(O)C(C)(C)C([C@@H](OC(C)=O)C(=O)[C@]3(C)[C@@H](O)C[C@]1(OC2)[H])=C(C)[C@@H](OC([C@@H]([C@@H](NC(=O)C6=CC=CC=C6)C7=CC=CC=C7)OC(CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)=O)=O)C5)[H]
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

6918473