DGY-06-116

SKU: orb1306015

Description

DGY-06-116 is a potent, selective, and irreversible covalent inhibitor, demonstrating high potency against Src (IC50 = 3 nM) and weaker activity against FGFR1 (IC50 = 8340 nM). This small molecule is a valuable chemical probe for cancer research, facilitating the study of Src-dependent signaling pathways in both cellular and biochemical assays.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 2556836-50-9
• MW: 597.11
• Purity: 99.60% (May vary between batches)
• Formula: C₃₂H₃₃ClN₈O₂
• SMILES: CN1CCN(CC1)c1ccc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)c(Nc3ccccc3NC(=O)C=C)n2)cc1
• Target: FGFR,Src
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (6.7 mM);DMSO:100 mg/mL (167.47 mM)

Bioactivity

• Target IC50:
  Src:3nM |FGFR1:8340 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DGY 06 116, DGY06116, DGY-06-116, FGFR1, Src

Compound Identifiers

PubChem CID

154573782