DGKζ-IN-6

SKU: orb2695689

Description

DGKζ-IN-6 (compound 40) is a potent and orally bioavailable DGKζ inhibitor with an IC50 of 45.5 nM. It suppresses IL-2 secretion and is a valuable research tool for studying T-cell activation in the context of cancer and autoimmune disease research, as evidenced in cellular assays.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 3058005-75-4
• MW: 440.49
• Formula: C₂₂H₂₁FN₄O₃S
• SMILES: O=C(N)C(N(C1=NC(N)=C(S1)C(=O)C2=CC=C(OC3CC3)C=C2)C4=CC=C(F)C=C4)C
• Target: Interleukin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172652616