DGKζ-IN-10

SKU: orb2945915

Description

DGKζ-IN-10 (compound 349) is a potent and selective small molecule inhibitor of diacylglycerol kinase zeta (DGKζ), exhibiting an IC50 value of ≤200 nM. This tool compound enables the study of DGKζ's role in immune cell signaling, T-cell anergy, and cancer biology in both cellular and biochemical assays.

Key Properties

• CAS Number: 3062708-86-2
• MW: 461.511
• Formula: C₂₄H₂₀FN₅O₂S
• SMILES: N([C@@H](C(N)=O)C)(C=1SC(C(=O)C=2C=CC(=NC2)C3=CC=CC=C3)=C(N)N1)C4=CC=C(F)C=C4
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172677421