DGAT1-IN-1

SKU: orb1308389

Description

DGAT1-IN-1 is a highly potent and selective small molecule inhibitor of diacylglycerol O-acyltransferase 1 (DGAT1), exhibiting an IC50 value below 10 nM. This compound is a valuable research tool for investigating lipid metabolism, obesity, and metabolic diseases in both cellular and animal models.

Research Area

Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 1449779-49-0
• MW: 551.56
• Purity: 99.15% (May vary between batches)
• Formula: C₃₀H₂₈F₃N₃O₄
• SMILES: OC(=O)C[C@H]1CC[C@@H](CC1)c1ccc(cc1)-c1ccc2nc(cn2c1)C(=O)NCc1ccc(OC(F)(F)F)cc1
• Target: Transferase
• Solubility: DMSO:20 mg/mL (36.26 mM)

Bioactivity

• Target IC50:
  DGAT-1:< 10 nM
• In Vitro:
  DGAT1 inhibitor Imidazopyridine and imidazothiazole compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, mono- acylglycerol acyltransferase, inhibit, acyl-CoA:cholesterol acyltransferase, Acyltransferase, Diacylglycerol acyltransferase, DGAT1IN1, DGAT-1-IN-1, DGAT1-IN-1, DGAT1, DGAT1 IN 1, Diglyceride acyltransferase

Compound Identifiers

PubChem CID

71696573