Dexketoprofen trometamol

SKU: orb1298215

Description

Dexketoprofen trometamol is a fast-acting, non-selective cyclooxygenase (COX) inhibitor available for oral and parenteral use. It is utilized in pharmacological research to study inflammatory and pain pathways, with applications in both in vitro enzyme assays and in vivo models of analgesia and inflammation.

Research Area

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 156604-79-4
• MW: 375.42
• Purity: 99.97% (May vary between batches)
• Formula: C₂₀H₂₅NO₆
• SMILES: NC(CO)(CO)CO.C[C@H](C(O)=O)c1cccc(c1)C(=O)c1ccccc1
• Target: COX
• Solubility: H2O:15 mg/mL (39.96 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.33 mM)

Bioactivity

• In Vivo:
  Dexketoprofen trometamol appears to provide similar analgesic efficacy to COX-2 inhibitors when used to treat acute pain, has a rapid onset of action, is well tolerated, and has an opioid-sparing effect when used as part of a multimodal regimen in the acute pain setting.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Dexketoprofen trometamol, COX-2

Compound Identifiers

PubChem CID

6918332