Desonide

SKU: orb1309538

Description

Desonide (Prednacinolone) is a synthetic topical glucocorticoid that exerts anti-inflammatory effects by activating glucocorticoid receptors. This activation modulates gene transcription, leading to the production of proteins like lipocortin-1 that inhibit key inflammatory pathways. It is widely used in research models, both in vitro and in vivo, to study steroid-mediated inflammation and immune responses.

Research Area

Cell Biology, Metabolism Research, Neuroscience

Key Properties

• CAS Number: 638-94-8
• MW: 416.51
• Purity: 99.74% (May vary between batches)
• Formula: C₂₄H₃₂O₆
• SMILES: [H][C@@]12C[C@@]3([H])[C@]4([H])CCC5=CC(=O)C=C[C@]5(C)[C@@]4([H])[C@@H](O)C[C@]3(C)[C@@]1(OC(C)(C)O2)C(=O)CO
• Target: Apoptosis,Huntingtin,Glucocorticoid Receptor
• Solubility: Ethanol:28 mg/mL (67.23 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (6 mM);DMSO:55 mg/mL (132.05 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, GlucocorticoidReceptor, Glucocorticoid Receptor, Locapred, inhibit, Desonide, Tridesilon, Prednacinolone

Compound Identifiers

PubChem CID

5311066