Desmethylazelastine

• Catalog Number: orb1982811
• Category: Small Molecules
• Description: Desmethylazelastine, the primary active metabolite of Azelastine, undergoes oxidative metabolism via the cytochrome P450 enzyme system, exhibits a 97% protein binding rate, and has an elimination half-life of 54 hours. Azelastine, an orally active, selective, and high-affinity histamine H1-receptor antagonist, is utilized in the research of allergic rhinitis, asthma, diabetic hyperlipidemia, and SARS-CoV-2 [1] [2] [3] [4] [5].
• Purity: 98.00%
• MW: 367.87
• Biological Activity: Desmethylazelastine, the primary active metabolite of Azelastine, undergoes oxidative metabolism via the cytochrome P450 enzyme system, exhibits a 97% protein binding rate, and has an elimination half-life of 54 hours. Azelastine, an orally active, selective, and high-affinity histamine H1-receptor antagonist, is utilized in the research of allergic rhinitis, asthma, diabetic hyperlipidemia, and SARS-CoV-2 [1] [2] [3] [4] [5].
• CAS Number: 47491-38-3
• Formula: C₂₁H₂₂ClN₃O
• SMILES: Clc1ccc(Cc2nn(C3CCCNCC3)c(=O)c3ccccc23)cc1
• Storage: -20°C
• Note: For research use only