Desethylamiodarone hydrochloride

SKU: orb1992892

Description

Desethylamiodarone hydrochloride is the primary active metabolite of amiodarone, generated via CYP3A metabolism. It functions as an antiarrhythmic agent by inhibiting ATP-sensitive potassium channels with an IC50 of 19.1 µM. This compound is a key tool for investigating amiodarone's pharmacokinetics and cardiotoxicity in cardiovascular research models.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 96027-74-6
• MW: 653.72
• Formula: C₂₃H₂₆ClI₂NO₃
• SMILES: Cl.CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCNCC)c(I)c1
• Target: Autophagy,Others,Potassium Channel

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

178801