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Desethylamiodarone hydrochloride

SKU: orb1992892

Description

Desethylamiodarone hydrochloride is the primary active metabolite of amiodarone, generated via CYP3A metabolism. It functions as an antiarrhythmic agent by inhibiting ATP-sensitive potassium channels with an IC50 of 19.1 µM. This compound is a key tool for investigating amiodarone's pharmacokinetics and cardiotoxicity in cardiovascular research models.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number96027-74-6
MW653.72
FormulaC23H26ClI2NO3
SMILESCl.CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCNCC)c(I)c1
TargetAutophagy,Others,Potassium Channel

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Desethylamiodarone hydrochloride (orb1992892)

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