Des His1, Glu8 Exendin-4

• Catalog Number: orb1981155
• Category: Small Molecules
• Description: Des His1, Glu8 Exendin-4 is a glucagon-like peptide-1 receptor (GLP-1-R) antagonist that regulates blood glucose. Des His1, Glu8 Exendin-4 is used in the study of diabetes and obesity.
• Purity: 99.92%
• MW: 4063.46
• SMILES: [H]NCC(N[C@H](C(NCC(N[C@]([H])(C(N[C@@H](CC1=CC=CC=C1)C(N[C@]([H])(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCSC)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](C)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@]([H])(C(N[C@H](C(N[C@@H](CC3=CNC4=C3C=CC=C4)C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(NCC(N5CCC[C@H]5C(N[C@H](C(N[C@H](C(NCC(N[C@@H](C)C(N6CCC[C@H]6C(N7CCC[C@H]7C(N8CCC[C@H]8C(N[C@H](C(N)=O)CO)=O)=O)=O)=O)=O)=O)CO)=O)CO)=O)=O)=O)=O)CC(N)=O)=O)CCCCN)=O)CC(C)C)=O)=O)CCC(O)=O)=O)[C@@H](C)CC)=O)=O)CC(C)C)=O)CCCNC(N)=N)=O)C(C)C)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)=O)CCC(N)=O)=O)CCCCN)=O)CO)=O)CC(C)C)=O)CCC(O)=O)=O)CO)=O)[C@H](O)C)=O)=O)[C@H](O)C)=O)=O)CCC(O)=O)=O
• Formula: C₁₇₉H₂₇₇N₄₇O₅₉S
• Biological Activity: Des His1, Glu8 Exendin-4 is a potent antagonist of the glucagon-like peptide-1 receptor (GLP-1-R), enhancing glucose homeostasis through the dual regulation of insulin secretion and glucose production. This compound is employed in research on type 2 diabetes and gastrointestinal disorders [1].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.