Deoxylapachol

SKU: orb1297398

Description

Deoxylapachol is a natural product exhibiting potent antifungal activity against key wood-decay fungi, including brown rot and white rot species, by inducing cell wall stress. This compound serves as a valuable research tool for studying fungal physiology and developing novel wood preservatives in both in vitro and material protection assays.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 3568-90-9
• MW: 226.27
• Purity: 99.53% (May vary between batches)
• Formula: C₁₅H₁₄O₂
• SMILES: CC(C)=CCC1=CC(=O)c2ccccc2C1=O
• Target: Antifungal,Antifection
• Solubility: DMSO:95 mg/mL (419.85 mM)

Bioactivity

• Target IC50:
  P388 leukemia cells:0.6 microgm/ml
• In Vitro:
  Teak ( Tectona grandis L.f., Verbenaceae) sawdust extract inhibited the growth of Aspergillus niger. By (1)H-NMR the active compounds were identified as Deoxylapachol and tectoquinone. Two A. niger transgenic strains which show induction of 1,3 -alpha-D-glucan synthase were used as a cell wall damage model. Deoxylapachol is active against P-388 leukemia cells with IC50 of 0.6 microgm/ml).
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Deoxylapachol, Antifungal, Antifection, inhibit, Fungal, Inhibitor

Compound Identifiers

PubChem CID

97448