DENV-IN-15

SKU: orb3210974

Description

DENV-IN-15 is a sulfonyl anthranilic acid derivative and a pan-serotype anti-dengue virus (DENV) inhibitor with broad-spectrum RNA virus activity. It has an EC50 of 0.7 μM against DENV-2 in Huh-7 cells. DENV-IN-15 selectively regulates the translation process of mRNA encoding translation-related proteins with a 5' oligopyrimidine motif and reduces the expression of specific ribosomal proteins, thereby inhibiting viral replication. Additionally, DENV-IN-15 enhances membrane permeability, human plasma stability, and human liver microsomal metabolic stability. It is useful for research related to dengue virus infection.

Key Properties

• Target: Anti-infection

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Anti-infection