Demethyleneberberine

SKU: orb1222455

Description

Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria either in vitro or in vivo.Demethyleneberberine suppresses CYP2E1, hypoxia inducible factor α, and inducible nitric oxide synthase, which contributes to oxidative stress and restored sirtuin 1/AMP-activated protein kinase/peroxisome proliferator-activated receptor-γ coactivator-1α pathway-associated fatty acid oxidation in chronic ethanol-fed mice.

Key Properties

• CAS Number: 25459-91-0
• MW: 324.35
• Purity: >98% (HPLC)
• Formula: C₁₉H₁₈NO₄+
• SMILES: Oc1cc2c3cc4ccc(OC)c(OC)c4c[n+]3CCc2cc1O
• Target: Akt
• Solubility: In Vitro: DMSO : 10 mg/mL (30.83 mMul)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Akt