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Demethoxycurcumin

SKU: orb1300195

Description

Demethoxycurcumin is a bioactive curcuminoid with demonstrated antioxidant, anti-inflammatory, and anti-proliferative properties. It exhibits anti-acanthamoebic effects and shows potential as a combination therapy in drug-resistant cancers, notably by activating AMPK to inhibit metabolic and oncogenic pathways in triple-negative breast cancer cells in vitro.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Neuroscience

Images & Validation

Key Properties

CAS Number22608-11-3
MW338.35
Purity98.10% (May vary between batches)
FormulaC20H18O5
SMILESCOc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)cc2)ccc1O
TargetAntioxidant|||Apoptosis|||Autophagy|||Antibacterial
SolubilityDMSO:112.5 mg/mL (332.5 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (7.39 mM)

Bioactivity

Target IC50
BACE1:17 μM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Demethoxycurcumin, Desmethoxycurcumin, Curcumin II, Autophagy, Bacterial, Apoptosis, Antioxidant, Monodemethoxycurcumin

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

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1 ml x 10 mM (in DMSO)
$ 90.00
20 mg
$ 110.00
50 mg
$ 200.00
DispatchUsually dispatched within 5-10 working days
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