Deltonin

SKU: orb1303674

Description

Deltonin is a bioactive small molecule that inhibits ERK1/2 and AKT signaling pathways. It demonstrates cytotoxic activity in vitro against various cancer cell lines, including HepG2, C26, and MDA-MB-231 cells, supporting its research use in oncology and signal transduction studies.

Research Area

Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 55659-75-1
• MW: 885.04
• Purity: 99.79% (May vary between batches)
• Formula: C₄₅H₇₂O₁₇
• SMILES: [H][C@]12C[C@@]3([H])[C@]4([H])CC=C5C[C@H](CC[C@]5(C)[C@@]4([H])CC[C@]3(C)[C@@]1([H])[C@H](C)[C@@]1(CC[C@@H](C)CO1)O2)O[C@]1([H])O[C@H](CO)[C@@H](O[C@]2([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@]1([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O
• Target: Endogenous Metabolite,Akt,ERK
• Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:100 mg/mL (112.99 mM)

Bioactivity

• Target IC50:
  C26 cells (mouse):1.22 μM|MDA-MB-231 cells (human):1.58 μM|HepG2 cells:7.66 μM

Storage & Handling

• Storage: keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Akt, Endogenous Metabolite, Deltonin, inhibit, Extracellular signal regulated kinases, EndogenousMetabolite, ERK, Inhibitor, PKB, Protein kinase B

Compound Identifiers

PubChem CID

441884