Delphinidin 3-glucoside chloride

SKU: orb2279176

Description

Delphinidin-3-O-glucoside chloride, a phenolic compound from Hibiscus sabdariffa, exhibits antioxidant and antitumor properties. It demonstrates pro-apoptotic effects in B-cell chronic lymphocytic leukemia (B-CLL) in vitro and inhibits platelet aggregation and EGFR signaling, potentially via pathways involving pAKT and IRF1.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 6906-38-3
• MW: 500.84
• Purity: >99.99% (May vary between batches)
• Formula: C₂₁H₂₁ClO₁₂
• SMILES: C1=C(C=C(C(=C1O)O)O)C2=[O+]C3=CC(=CC(=C3C=C2O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)O.[Cl-]
• Target: EGFR,Apoptosis,Akt

Bioactivity

• Target IC50:
  EGFR:2.37 µM
• In Vivo:
  In the MDA-MB-231-Luc-GFP xenografted athymic BALB/c mice model, Delphinidin 3-glucoside chloride (40 mg/kg/day; i.g., for 25 days) inhibited tumor growth.
• In Vitro:
  Delphinidin 3-glucoside chloride (30-100 μM; 24 h) induces cell apoptosis.

Storage & Handling

• Storage: keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Delphinidin 3glucoside chloride, Delphinidin-3-O-glucoside chloride, Delphinidin 3-glucoside Chloride, Delphinidin 3 glucoside chloride, Apoptosis, EGFR

Compound Identifiers

PubChem CID

165558