Dehydrodiisoeugenol

SKU: orb1300206

Description

Dehydrodiisoeugenol exhibits anti-inflammatory properties by suppressing LPS-induced COX-2 expression in RAW264.7 macrophages. It functions through inhibiting IκB-α degradation and NF-κB transcriptional activity, making it a useful research tool for studying inflammation pathways in vitro.

Research Area

Immunology & Inflammation, Infectious Disease & Virology, Neuroscience, Signal Transduction

Key Properties

• CAS Number: 2680-81-1
• MW: 326.39
• Purity: 99.97% (May vary between batches)
• Formula: C₂₀H₂₂O₄
• SMILES: COc1cc(\C=C\C)cc2C(C)C(Oc12)c1ccc(O)c(OC)c1
• Target: COX,NF-κB,Antibacterial
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.13 mM);DMSO:59 mg/mL (180.77 mM);Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cyclooxygenase, COX, Dehydrodiisoeugenol, Bacterial, Inhibitor, inhibit, Nuclear factor-kappaB, Nuclear factor-κB, NF-kB, NFkB, NFκB, NF-κB

Compound Identifiers

PubChem CID

5379033